Source: Beijing News
Author: Zhang Tiancha
On December 31, 2022, the latest data released by the US Centers for Disease Control and Prevention showed that XBB.1.5 accounted for 41%of the cases of crown diseases in the United States, and has replaced the advantages of BQ.1.1 and BQ.1, becoming the number one popular in the United States, which is popular in the United States.Poison.
XBB.1 and XBB.1.5 are the sub -branches of XBB.In August 2022, India first appeared in the Omikon XBB mutant, and then spread quickly, and soon became the main popular plants in Singapore, Malaysia and other countries.Since then, XBB mutations have gradually evolved into Omikonia branches, including XBB.1 and XBB.1.5.
XBB's pathogenic force has not significantly enhanced
Now, XBB has also appeared in China.
Xu Wenbo, director of the China Centers for Disease Control and Control Center, introduced that BF.7, BQ.1, and XBB have been introduced to China in the past three months.In China, BQ.1 and its sub -branches were detected in 49 cases of nine provinces, and XBB Asian branches were detected in 11 cases of 11 provinces.
As XBB and its sub -branches XBB.1 and XBB.1.5 appear globally and China, some news said that these mutant plants mainly attack the cardiovascular and cerebrovascular and digestive systems, which can easily cause diarrhea.Therefore, there is a tide of drug grabbing, enteritis, menglone scattered, norfloxacin capsules, lactate tablets, etc.
Buying drugs is understandable.However, other cases also need to be considered.First, whether the XBB and its sub -branches can cause cardiovascular and cerebrovascular and digestive symptoms, there are no exact clinical evidence; the second is that even if you need to take medicine, you need to take medicine under the guidance of a doctor and avoid medication by yourself.
The key question is that XBB and its sub -branches need to be clear about the current outbreak and how much harm to people are.
In terms of the current situation, XBB is only an enhanced immune escape, but the symptoms are not serious, and the mortality rate is not high. Therefore, it is not necessary to worry about XBB and its sub -branches.
As the result of the sequencing of the virus strain extracted from the infected person in China, domestic infections are still based on Omikon's BA.5.2, BF.7 subtypes as the main pathogen.The source of the Lord's infection also needs to observe.But even so, XBB and its sub -branches are unlikely to rise more than BA.5.2 and BF.7 manufacturing.
According to the clinical situation of other countries now, such as the situation in the United States, the pathogenesis of XBB and its sub -branches has not significantly enhanced. The symptoms of people after infection are similar to the symptoms caused by other subtypes caused by Omikon.Even the symptoms are lighter, and the mortality rate has not increased.If the virus variants are regarded as a normal state, XBB is just a normal mutant strain of Omikon.
Still need to be alert to XBB's infection
It still needs to be noted that XBB has a special mutation.Related studies have shown that XBB.1.5 is different from the strains of the same family. It has an additional key mutation F486P, which is more affinity with human vascular tension enzyme conversion enzyme 2 (ACE2).This makes XBB.1.5 mutant strains more likely to invade human cells.
The result of the following is that XBB.1.5 has a higher immune escape ability.In other words, even if the vaccine is vaccinated, whether it is an active vaccine or a mRNA vaccine, the immune protection force for the mutant strain may decrease, that is, XBB.1.5 is more likely to cause infection than other strains.
At the same time, the natural infection virus is equivalent to vaccination, which will produce neutralized antibodies in the body. However, as XBB.1.5's immune escape ability is enhanced, the immunity obtained after natural infection may also decrease, and it is difficult to block XBB.1.5 infection.However, small molecular antiviral drugs are also effective for XBB.1.5.
These situations can also be explained from the mutation of the virus.The changes are inseparable from its ancestors. Even the XBB and its sub -branches are derived from the mutant strains of Omircor.
So far, there are only 5 variants that need to be concerned by the World Health Organization.The World Health Organization upgraded the Omikon mutant strains on November 26, 2021 to the current popular concern.
At present, Omikon's mutant strains are constantly mutating. The World Health Organization observes shows that at least hundreds of Asian branches in Omikon are mutant.XBB is just a small branch of Omikon. The evidence currently observed is that its pathogenicity and mortality rate are not strong, but the immune escape ability has increased.
For this situation, it is necessary to prevent secondary infections, especially XBB.1.5 may cause secondary infection.However, most of the existing secondary infections (not necessarily caused by XBB.1.5) indicate that their symptoms are lighter than the first time.
Avoid infections caused by secondary infections and XBB.1.5, the best way is to take vaccination to strengthen needle vaccines.Of course, if you have just been infected with vaccination, you can wait for four to six months before taking the second needle to strengthen the needle.In addition, pay attention to self -protection around the Spring Festival, wear masks, wash hands, etc.
In addition, it is necessary to remind that after the infection, fever will not retreat, difficulty breathing, and more severe nausea, vomiting, diarrhea and other digestive system symptoms. The mental state is not good.
We have experienced strong winds and waves. On the basis of doing good protection and preparation, we don't need to worry too much.
