Is the rise in temperature help relieve the new crown virus epidemic?Yale University professor of immunology at the University recently told Caixin reporter that there is no scientific evidence that the temperature and the virus are inevitable.Epidemia is mostly in winter. Weather warming often reduces the speed of infection. The reason is that after the temperature rises, indoor ventilation and people's outdoor activities increase. With the power of natural power, the concentration of the virus can be diluted, and the chance of transmission can be reduced.He then believes that the current strategy of resistance should be shifted from the emphasis on the closure of the home to the encouraging outdoor activities that encourage people to be empty, and open public spaces such as parks.
The virus is equivalent to parasites and needs to find the host to survive.In the case of no particularly effective treatment, the anti -virus is not allowed to invade the human body, and the other is to rely on autoimmunity.Displaying Ping said that since the new crown epidemic, 70%of the infected patients have been infected.This is because people are in the room in winter and are easy to spread close.As the weather is warmer, opening the windows to ventilate and increase outdoor activities will help the virus dilution, and the ultraviolet rays in the sun itself are also conducive to killing the virus.
Shiping is currently serving as a professor and immunology professor at the UTC Cancer Studies of Yale University in the United States. He has long been engaged in the research of basic immunology mechanisms and tumor immunotherapy. It was the first method for antibody to block PD-1/PD-L1 pathway.It is the industry's recognized immunology authority.
From the perspective of immunology, most of the new crown patients (about 85%-90%) are mild and medium, and they can heal themselves by self-immunity; there are some cases that are transformed into severe diseases.He is an older and basic patient.There are also a small number of cases that cause inflammatory storms that are excessive immune. While fighting the virus, it causes organs to damage or even fail.
In the absence of vaccines and special effects drugs, Duo Ping said that an important direction to prevent infection is to improve the human body's natural immunity, antibodies in the human body, neutral granulocytes, macrophages, and many cytokines, and many cytokines.In the early days of virus invasion, it often plays a great role. If it is mild, you can carry it.One of the basic ways to increase natural immunity is to exercise, fever during fitness, accelerate blood circulation, and increase natural immunity.Duo Ping said that it has not been well discussed for the natural immunization prevention new crown, but it is necessary to discuss it, but it is a good way to adhere to outdoor sports, but maintaining a certain social distance.
For the research and development of the new coronary vaccine, Shi Ping said that the prospects were not very optimistic.In his opinion, the new crown virus has a high self -healing rate. There are only about 10%of the people who really benefit from the vaccine. In principle, the treatment method is better, or the combination of treatment with the vaccine.
The clinical trial of vaccine is a major bottleneck. A clinical trial must be effective and safe, and it takes a long time.For the new coronal virus, because the test object has its own immunity, only 10 or less vaccine may be effective in 100 people, so it requires thousands of people to test.Because the trials are high -risk groups, they also have ethical difficulties themselves.Exhibit as an example that AIDS has encountered similar problems in R & D vaccine. The vaccine completed tests are susceptible people in Africa, giving an active adolescent test vaccine.Develop a successful vaccine.The cycle of the new crown vaccine research and development experiment generally requires one to one and a half years to get preliminary clinical results, and it may not be able to get positive results, which is meaningless.
For the influenza vaccine that has been widely used at present, the display is frankly stated that the effect is not ideal. This is because the variation of the flu virus is relatively large. The protein on the flu virus often changes.Popular viruses, based on different changes, prepare vaccines, pick out the possibilities first injection. There are speculative components in it, and the effectiveness is not ideal.Therefore, although there are vaccines, influenza comes every year.Compared with influenza viruses, the current variation of the new coronal virus is not great, and it may be relatively better.
For Rydecwie, who entered clinical trials and was nicknamed the people, Dangping said that its principle is to inhibit the synthetase of RNA. When the disease is not very serious, the virus replication is inhibited.It's like being bitten by a poisonous snake. Before damaging the nervous system, detoxification drugs are effective.If the virus has caused great damage, it is not very good, so its applicable population will be mainly mild, preventing patients from evolving into intensive illness.He also admits that it is not easy for the clinical design of Chinese minor drugs.Because most patients will heal themselves, the proportion of severe illness is very small, so the size of the experimental population is very large.The management of the control group is not easy to do, because once the disease progresses, it cannot be carried ethically, and other measures or drugs need to be used. This will interfere with the result and is also a problem.Generally speaking, the medicine that is prone to clear results is for severe drugs, because patients do not have too many other ways, they are less interference, and it is easy to judge the effect of medication.
As for the treatment of plasma antibodies of rehabilitation patients in China, Dangping said that this is the most primitive method of immunology. The principle is that the blood of patients with blood has antibodies.But this is only applicable to individual examples, and is widely used.There are often many antibodies in the healing patient's plasma, and patients may have other diseases, cross -infections, etc.Now the method of genetic engineering can be used in large quantities of reorganization antibodies, and security is guaranteed.The disadvantage of antibody treatment is that the effect is not long, because the antibody can only exist in the body for several weeks, and it is impossible to produce lasting protection.
Where will the new crown virus infection go in the future?In addition to the development of vaccines and special effects drugs, the virus also has the possibility of gradually weaker or disappearing during the spread of transmission. Many viruses disappear, because from the perspective of the evolution of the virus, only weakening can obtain wider spread.The strong virus killed the host and died at the same time.As for the group immunity mentioned by the United Kingdom and Germany, Display said that a large number of infected people in the crowd, forming immunity to prevent the virus further spread. This is the original method, that is, there is no way to do it.Modern medicine will still provide symptomatic treatment as much as possible to help patients get time, and finally clean up the virus by the immune system.
