Li Yuexia
In more than three weeks of the "Omikon" case, 90 countries and regions have found related cases. The world's various countries that have previously issued the "violent offensive" of the Delta variant strains have issued an inbound restriction order and imposed epidemic prevention measures for domestic activities. Data show that although the most of the New Booth strains of Omikon Rongxin, the World Health Organization emphasized that experts have a shallow understanding of this new strain.So you cannot lightly enemy. Seven Kingdoms Group also issued a statement warning on Thursday that Omikon is "the biggest threat of the world's current public health", and the strengthening of cooperation in various countries is urgent.
After South Africa notified the first Omikon case on November 24, as of December 17, the new variant strain in the crown disease has been in 90 countriesAnd the region spread.There are cases of confirmation of Omikon in more than 30 European countries, and related cases in at least 20 countries and regions in the Asia -Pacific region have also appeared, including Singapore, Malaysia, China and other places.
The World Health Organization listed this variant strain number B.1.1.1.529 on November 26 as the "must be concerned" and used the 15th Greek alphabet "Omikon".(Omitron) Name.
The panic caused by this variant's strain caused the stock market to fall sharply and oil prices collapsed.The WHO immediately reminded countries not to implement restrictions on entry restrictions because of Omikon's warehouse.However, all continents have successively implemented entry measures to passengers from southern Africa.
Popular diseaseologists warned at the time that it was too late to restrict travel and could not prevent Omikon from spreading globally.Omikon spread widely within a few weeks, confirming this prediction of experts.
In addition to entry restrictions, Europe, Asia and other countries and regions have also shifted focus to curbing Omikon to spread in the community, restore the implementation of masks, stipulate store business hours, restrict the number of parties, restaurant halls, restaurant halls.Waiting for measures.
The Briefing released by the WHO on December 10 pointed out that Omikon spread faster than Delta, but the symptoms may not be like the symptoms caused by Delta's strains.
or replaced Delta into the most important virus in Europe
However, the Britain reported at least one person on December 13 and died.The world ’s first Omicorr death case has appeared in the world.Britain has reported more than 10,000 Omikon cases so far, and at least 10 people have been hospitalized. Most of the patients have vaccinated two doses of vaccine.
The European Disease Prevention and Control Center predicts that in the first two months of next year, Omikon may replace Delta and become the most important virus strain in Europe.Vaste, the Prime Minister of France, another heavy epidemic area in Europe, described that Omikon's spread in Europe is like "lightning", saying that Omikon will become the main strain spread in France in early 2022.There are more than 30 states in the United States.This has led to whether the vaccine can resist this new strain to become a topic that people are more concerned about.
Preliminary evidence shows that the effectiveness of the existing vaccine has decreased to prevent the effectiveness of the infection and spread of Omiko's strain.However, due to the limited number of samples and related research, the WHO has called on countries to strengthen monitoring and sequencing work.
The WHO also called on countries not to lightly enemy, and said that the vaccine alone could not cope with the virus.However, Fuqi, the top of the US top infectious diseases, director of the Institute of Allergic and Infectious Diseases, said on the 15th that the vaccine and enhanced needle can still resist Omikon without developing new vaccines.
It is worrying that the vaccine developed by the American pharmaceutical Morlum Pfizer and the German Biosteen -based Biontech (Biontech), which was developed by the German biotechnology company (Biontech), against the effective efficiency of Omikdon after two doses, fell to 33% to 33%.EssenceHowever, the data from South Africa said that after two stitches, the above vaccines were still effective in preventing Omikon infected with hospitalization, which reflects that the vaccine is still effective in preventing the hospitalization of patients with severe illnesses and high -risk patients.
Studies in cooperation with Swiss researchers in the United States show that in the face of Omikon, the protection of various vaccines is uneven.Researchers at the University of Washington and Swiss pharmaceutical Humabs Biomed SA analyzed the effects of six vaccines for high -contagious and highly mutated Omikon.Bloomberg quoted on the 17th that only three of the 13 people who vaccinated the two doses of the Chinese medicine vaccine had a neutral antibody against Omikon.For Johnson & Johnson vaccine, this indicator dropped to one of 12 people.Among the 11 people who completely inoculated the Russian satellite V vaccine, no one had antibodies that could neutralize Omikon.
This unrelated study has also found that the lowest degree of protective antibody decreases is the combination of previously infected with crown disease and inoculation of two doses of Pfizer MRNA vaccine.
Another anti -epidemic tool, that is, the utility of the drug is more concerned because of the emergence of new virus strains.Pfizer announced on the 14th that the experiment showed that oral medication Paxlovid was effective for Omikon.Pfizer has applied for urgent authorization for PaxLovid.In view of the rising infection rate and disease rate, the European Drug Administration issued an announcement on the 16th, suggesting that member states use PAXLOVID, which has not been authorized by the European Union in emergency situations.
Another pharmaceutical dealer Merck (Merck) also developed an export of medicine "Molnupiravir" to apply for emergency authorization earlier, but the medicine effective in the clinical trials of high -risk patients effectiveNot good, only 30 % of the number of hospitalizations and deaths was reduced.
Expert: Omikon Delta and the flu in the United States may be "three consecutive strikes"
South Africa did not because of the Omikon variable poison strainsAnd more patients with severe illnesses have increased, but the death cases caused by Omikon are lower.
The majority of Omikon infected people are mild, and the factors may include they have vaccinated or have been infected with crown disease.Scientists believe that more data of Omikon patients can be analyzed in order to have a deeper understanding of the harm of this variant, especially for patients who have been old, have not vaccinated vaccines, and have never been contaminated.
However, because the northern hemisphere is already in the cold climate of popular colds, the scene painted by the American Disease Control and Prevention Center on the 14th is worrying.One possible situation is that Omikon spreads in the United States, and Delta's strains and flu raging at the same time, causing the United States to face the "three consecutive strikes", and may completely overwhelm the medical system.The second situation is that the scale of outbreaks is much smaller until next spring, but experts are not sure which situation is more likely.
The Washington Post pointed out that the data shows that Omikon's confirmed cases have risen seven times in a week, and this rate will exacerbate the pressure of many health systems.No fever.
Paul Burton, chief medical officer of American pharmaceutical dealer Moderna, has recently raised another concern.He pointed out that in the future, he may now be the super variant of Omikona Gaderta.He recently warned that if there were patients infected with Ottacong and Delta mutant strains at the same time, they would likely exchange deoxyuraotrophosis (DNA) in the infected cells, and then another new type of super variants were derived.He pointed out that crown disease infection usually involves only one variant strain, but in a few cases, patients may be infected with two strains at the same time, and many infections in the UK currently have many infected Delta and Austria.The case of MCOP makes this situation very likely.
The WHO urged countries to coordinate policy in response to mutations
Faced with strong enemies who are still difficult to find out, WHO hopes that countries have regulated plans and coordinate policies to cope with virus mutations.Come.
The confirmed cases of South Korea have continued to rise, and the number of Omiko cases has increased. The South Korean government recently considers other prevention and control measures for the suspension of "coexisting with crown diseases" strategies.
coexist with the virus or clear the challenge
Hong Kong respiratory system specialist Liang Zi Super to Hong Kong Zhongtong News Agency pointed out that due to the comparison of communication speedFast, Omikon is indeed a more dangerous virus, which will put a lot of pressure on the local medical system for countries that adopt a "coexistence with the virus" policy.
The speed of Omikon's spread has also made countries and regions adopt a "clear zero policy" in terms of prevention and blocking.In this regard, Liang Wannian, the leader of the expert group of the National Health and Health Commission's epidemic, explained in Beijing that "dynamic clearance" is not the pursuit of "zero infection", not allowing the development of the epidemic, but the pursuit of the epidemic situation as soon as possible.He said that the connotation of "dynamic clearance" is to alleviate the epidemic through active screening, adopting public health and social intervention measures, and effective treatment.
Kerhoff, the person in charge of the group technology of the WHO's epidemic, previously emphasized: "We are trying to support countries to make targeted response according to the situation, such as the population situation, the society between the government and the public and the people of the peopleContract relationships, policy implementation, etc. These reactions are not static, because the virus is constantly changing. Once spreading, it does not mean that it will always spread with this intensity. "
Harvard University in the United StatesWilliam Hanage, a epidemiologist, believes that it may take a few months to know the contagiousness of Omikon in the human body that has been vaccinated.
Virus and immunologists believe that Omikon sounded the alarm to the vaccine developer.Larry Corey, a virusist at the US Seattle Fredhainson Cancer Center, said: "Omikon let us recognize that crown diseases will not disappear, and we need better vaccines to deal with it."
Richard Friedland, president of South Africa's largest private hospital group NetCare, is optimistic."In fact, I saw the hope of the first line, which may indicate the end of the crown disease epidemic. It weaken to itself to be highly contagious, but it will not cause serious diseases ... Now, I am not so panicked."
The impact of the economy depends on the degree of harm of Omikon.Sithanonxay Suvannaphakdy, chief researcher at the Easov Issa East South Asia Research Institute in Singapore, pointed out that due to more international travel restrictions and more frequent blockades, at least in the short term, Omikon would make Yajian's internal and external and external.Commodity and service transactions have decreased.
Now it is too early to conclude that this Omircon poison's coffin covering the coffin is too early, but it may indeed be more contagious than the previous generations of variants, but not so fatal.
Bloomberg reports that this will help the world's normal state before the outbreak of the epidemic, which means that companies invest more funds in services.With the balance of expenditure, global economic growth is expected to increase from 4.7%to 5.1%from Bloomberg's economic research.
Hong Kong Study: Mild Omikon's symptoms
There are about 50 unseen mutations that have not been seen before, including crown diseases are used to attach to human cells on human cells32 mutations on SPike Protein.Among these 32 mutations can increase virus communication ability and mutations in the ability to escape vaccine.At present, most coronary vaccines are mainly targeted at spiny proteins covering the surface of the virus. Such mutations may cause problems with the protection of the vaccine.
A study of the University of Hong Kong found that the speed of Omikon's replication in the bronchial pipe is 70 times that of Delta's strains, which may be the reason why Omikhon spreads between people quickly.EssenceHowever, the replication speed of Omikon in the lung tissue is only one -tenth of the primitive strains, which means that it is possible to have mild symptoms after infection.The results increase the credibility of the early field observation results in South Africa.
Angelique Coetzee, chairman of the South African Medical Association, pointed out that the symptoms of Omikon infected people are "very mild", and some patients feel "extremely tired", physical pain and headacheEssence
Unlike Delta virus, so far, no patient has a sense of smell or taste loss, and no blood oxygen has decreased significantly.Most of the infected people of this variant strain are 40 years old or younger.
